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The COVID-19 vaccine

The information on this page has been gathered from DHEC (South Carolina Department of Health and Environmental Control) and the CDC (Centers for Disease Control).

If you are using software such as JAWS (Job Access With Speech) and have trouble accessing any of the pages on DHEC’s website that are linked to below, please try a different browser, such as Microsoft Edge or Apple Safari, if possible.

Vaccine availability, distribution and benefits

All South Carolinians 12+ are Eligible for COVID-19 Vaccines

DHEC Homebound Vaccination Program - available in all countines

The benefits of being fully vaccinated

COVID-19 Vaccine: ID and costs

COVID-19 and Vaccine Information

Before you get the vaccine

Before making an appointment to receive the COVID-19 vaccine, review the current health and safety recommendations from the CDC and/or your healthcare provider.

  • If you received passive antibody therapy treatment for COVID-19, wait 90 days after treatment to get the vaccine.
  • If you received another vaccine within the last 14 days, wait until 14 days after you received that vaccination to get the COVID-19 vaccine.
  • If you had a positive test for COVID-19, or your healthcare provider told you that you had COVID-19, do not get the vaccine until you have met the conditions for recovery, and until criteria have been met to discontinue isolation. Note, the CDC also states it is okay for an infected person to defer getting the vaccine for 90 days after symptoms have resolved based on low risk of reinfection during that period.
  • If you have been exposed to someone who tested positive for COVID-19, do not get the vaccine until after your quarantine period ends.

Making an appointment

When making an appointment, you may need to present credentials to verify you qualify to receive vaccination in that Phase. This includes providing some proof (e.g., badge, card, license, personalized letter from employer, picture of license). You may need to present the same credentials when receiving your scheduled vaccination.

DHEC maintains an updated list of vaccine providers.

Learn more about what to expect at your COVID-19 vaccination appointment.

Read the CDC’s COVID-19 Vaccines handout.

Finding a vaccine provider

  • Use DHEC’s vaccine locator to find locations offering the COVID-19 vaccine. Choose a location and call the phone number listed, or follow the link to the location’s website, to make an appointment.
  • Call DHEC’s Vaccine Information Line at 1-866-365-8110 for help finding a provider’s contact information. The Vaccine Inforamtion Line can’t schedule an appointment but can give you phone numbers for locations so you can call to make an appointment. It is avaialble from 7:00 am to 7:00 pm, seven days a week.

Frequently asked questions (FAQ)

Why should I get the vaccine?
According to the Centers for Disease Control (CDC), getting the COVID-19 vaccine provides additional protection that will help keep you safe, in addition to following recommended social distancing practices.

Do I still need to practice social distancing and wear a mask if I receive the vaccine?
Yes. According to the CDC, you should still wear a mask, practice social distancing, and wash your hands frequently even if you receive the vaccine.

I already had COVID-19 and recovered. Will the vaccine provide any benefit to me?
Yes. The CDC recommends you still receive the vaccine. For more information regarding your health, please talk to your primary care physician.

What are the most common side effects?
Some common side effects at the injection site include soreness, redness, or warmth to the touch. Some people report chills, fatigue, headache, or fever after getting the vaccine, especially the second dose. For more information about side effects of the vaccines approved for emergency use, visit the CDC's website.

How can I report any severe side effects or issues that I have?
When you receive the vaccine, you will be given information about where to report adverse effects, including the CDC’s new V-safe system. You can also complete a Vaccine Adverse Event Report System (VAERS) report online.

If you experience a severe allergic reaction, the FDA recommends you call 911 or go to the nearest hospital.

Can I get COVID-19 from the vaccine?
According to the CDC, no. None of the COVID-19 vaccines contain the live virus that causes COVID-19 so a COVID-19 vaccine cannot make you sick with COVID-19. The vaccine carries genetic material that allows your immune system to create antibodies that will combat the COVID-19 virus.

What can I do to protect myself from getting COVID-19 until I can get the vaccine?
Follow these recommendations:

How long do I have to wait before the vaccine is fully effective?
People are generally considered to be fully vaccinated (i.e., the vaccine is fully effective) two weeks after their second dose of the Pfizer or Moderna vaccine, or two weeks after receiving the single-dose Johnson & Johnson Janssen vaccine.

What can I do once I have been fully vaccinated?
The CDC provides extensive guidance for people who are fully vaccinated, including choosing indoor and outdoor activities and what to be aware of if you are considering domestic and international travel.

Is the COVID-19 vaccine free?
Vaccine doses purchased with U.S. taxpayer dollars will be given to the American people at no cost. However, vaccination providers may be able to charge administration fees for giving the shot. Vaccination providers can get this fee reimbursed by the patient’s public or private insurance company or, for uninsured patients, by the Health Resources and Services Administration’s Provider Relief Fund.

FAQs from DHEC

COVID-19 Vaccine Frequently Asked Questions

COVID-19 Vaccine: ID and costs

COVID-19 and Vaccine Information

COVID-19 Myths and Facts

COVID-19 Vaccine FAQs About Pregnancy and Fertility

Where to get more information

Visit DHEC’s website for Information about COVID-19 vaccination.

Call DHEC’s Vaccine Information Line at 1-866-365-8110 between 7:00 am and 7:00 pm, seven days a week.

Visit the CDC’s website for Key Things to Know About COVID-19 Vaccines.


The COVID-19 (Coronavirus) pandemic is an ongoing, rapidly changing situation. Please monitor publicly available information and always follow federal, state and local health organization guidance and government mandates. The information herein is intended to assist individuals with guidance about the COVID-19 vaccine.

The information provided herein is obtained from publicly available sources, including the CDC and DHEC. This information may vary and will be updated depending upon current situations. Due to the ever-chaning nature of the COVID-19 pandemic, be advised that SCCB gives no assurances as to the accuracy or completeness of the information provided. Further, the information contained herein is provided for general informational purposes only, and should not be construed as legal advice on any subject matter. Before relying on the information on this page, please check with DHEC, the CDC, or your healthcare provider to determine if there is additional, or more up-to-date, information.